The BRAIN Foundation Synchrony 2022 December 2 - 4 | 4141 Hacienda Dr, Pleasanton REGISTER NOW AGENDA
9:30 AM - 6:00 PM PST

December 2, 2022 - Roundtables

9:30 AM - 6:00 PM PST

Track 1

9:30 AM - 12:00 PM

NeuroInflammation - Working Group to create consensus article

Session Chair

Jennifer Frankovich, MD, MS

Clinical Professor, Dept of Pediatrics, Stanford Children’s Health
Lucile Packard Children’s Hospital Stanford

Elizabeth D. Mellins, MD, Stanford University
Judy A. Van De Water, PhD, UC Davis
Paul Ashwood, PhD, UC Davis
Harumi Jyonouchi, PhD, St. Peter’s University Hospital
Stephen J. Walker, PhD, Wake Forest Institute for Regenerative Medicine

9:30 AM - 6:00 PM PST

Track 2

9:30 AM - 12:00 PM

Pathways to FDA Approval - Challenges and Guidance

Session Chair

Gabriel Belfort, MD, PhD

Vice President, Clinical Development Sciences, Axial Therapeutics Inc.

Gabriel Belfort MD, PhD, Axial Therapeutics,
Kevin Sanders MD, Roche/Genentech
Gahan Pandina PhD, Janssen Research and Development
Robert H. Ring PhD, Kaerus Bioscience Ltd.
John Slattery, BioROSA Technologies
Joanna Sambor, MS, VP and Head of Regulatory at MapLight Therapeutics

12:00 PM - 4:00 PM

Pre-conference Outing: Livermore Wine Country

4:00 PM - 6:00 PM

Biomarkers to guide diagnosis and treatment

Session Chair

John Slattery

Co-founder, President & CEO, BioROSA

Manish Arora, BDS, MPH, PhD, Icahn School of Medicine at Mount Sinai
Karen J. Parker, PhD, Stanford University
Robert H. Ring, PhD, Kaerus Bioscience Ltd.
Kevin Sanders, MD, Roche/Genentech
Micheal Paul, PhD, MaraBio Systems Inc.

6:30 PM

Dinner: Dosa Party

9:00 AM - 6:00 PM PST

December 3, 2022


9:00 AM - 11:00 AM

Seizures in ASD

Session Chair

Richard Frye, MD, PhD

Phoenix Children’s Hospital and University of Arizona College of Medicine-Phoenix

11:00 AM - 2:40 PM PST

Research Presentations

11:00 AM - 11:20 AM

James Adams, PhD

Arizona State University

Microbiota Transplant for Pitt Hopkins

11:20 AM - 11:40 AM

Naveen Nagarajan, PhD

University of Utah

Microglia specific circuit defects in
repetitive form of ASD behaviors

11:40 AM - 12:00 PM

Stephen E.P. Smith, PhD

University of Washington

Identification of novel drug targets through the analysis of protein interaction network dysfunction

12:00 PM - 1:00 PM

Mexican Fusion Food Truck

1:00 PM - 1:20 PM

Brittany Needham, PhD

Stark Neurosciences Research Institute, IUSM

Gut microbial metabolites influence the brain and behavior in a preclinical and clinical ASD context

1:20 PM - 1:40 PM

Benjamin Marlow, MBiochem, ABPI, MBBS MRCPCH, PGCME

Cognition Health

Building on research success in Alzheimer’s to make an impact in the field of Autism

1:40 PM - 2:00 PM

Maude David, PhD

Oregon State University

Multi-omics, microbiome, and behavioral studies show the importance of fatty acids metabolism in Autism Spectrum Disorder

2:00 PM - 2:20 PM

Paul Song, MD

Vice Chairman and Senior Advisor at NKGen Biotch

The Regulatory Role of Natural Killer Cells in Neuroinflammation and its Potential Therapeutic Role in ASD

3:00 PM - 7:00 PM


9:00 AM - 5:00 PM PST

December 4, 2022 - Invited Speakers

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of CME Consultants and The BRAIN Foundation. CME Consultants is accredited by the ACCME to provide continuing medical education for physicians.

CME Consultants designates this live activity for a maximum of 6.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

9:00 AM - 9:15 AM

Pramila Srinivasan, PhD

President & Founder, The BRAIN Foundation

Opening Remarks

9:15 AM - 9:45 AM

Manish Arora, BDS, MPH, PhD

Edith J Baerwald Professor and Vice Chairman of the Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai

Harnessing the exposome to diagnose autism

9:45 AM - 10:15 AM

Richard Frye, MD, PhD

Phoenix Children’s Hospital and University of Arizona College of Medicine-Phoenix

Update on Mitochondrial Research

10:15 AM - 10:45 AM

T. Atilla Ceranoglu, MD

Director, Psychiatry Service, Shriners Hospital for Children Massachusetts Gen. Hospital, Boston, MA

Evaluation of Transcranial Photobiomodulation in Autism spectrum disorder: Double-blind, placebo-controlled, randomized clinical study of a novel approach

10:45 AM - 11:15 AM

John Gaitanis, MD

Pediatric Neurologist, Epileptologist, Hasbro Children’s Hospital

Medical Cannabis and Autism

11:15 AM - 11:30 AM


11:30 AM - 12:00 PM

Alessio Fasano, MD

Division Chief, Pediatric Gastroenterology and Nutrition
Director, Center for Celiac Research and Treatment
Director, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children

Evaluation of Zonulin Pathway for personalized treatment of Autism spectrum disorder using a humanized mouse model and human intestinal tissue

12:00 PM - 12:30 PM

Arthur Krigsman, MD

Pediatric Gastroenterologist
Private Practice, New York

Stephen Walker, PhD

Professor, Wake Forest Institute for Regenerative Medicine
Wake Forest School of Medicine

Improvement in Gastrointestinal Symptoms, Cognition and Behavior Upon Treatment of ASD- associated Enterocolitis

12:30 PM - 1:00 PM

Harumi Jyonouchi, MD

Allergy and Immunology
Saint Peter’s University Hospital

Biomarkers of Innate Immune Memory in Autism Spectrum Disorders

1:00 PM - 2:30 PM


3:00 PM - 3:30 PM

Joseph D. Buxbaum, PhD

Professor of Psychiatry, Neuroscience, Genetics and Genomic Sciences
Icahn School of Medicine at Mount Sinai

Does a Disrupted, Bidirectional Relationship Between Serotonin and Inflammatory Signaling Support ASD traits? Lessons from Model System Studies

3:30 PM - 4:00 PM

Randy Blakely, PhD

Executive Director, Stiles-Nicholson Brain Institute and Florida Atlantic University College of Medicine

Bidirectional Neuroinflammatory and Serotonin Signaling: Basic and Translational Perspectives

4:00 PM - 4:30 PM

Edward Quadros, PhD, SUNY

Professor, Department of Cell Biology
SUNY Downstate Health Sciences University

Folates, Folate Receptor Autoantibodies and the connection to Autism Spectrum Disorders